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IRF6 — PARP1

Text-mined interactions from Literome

Kogut et al., Mol Immunol 2007 : Using a Rap1-GTP pull-down assay, we found that FLG stimulation, but not LPS , of avian heterophils induced a rapid and transient Rap1 activation
Horváth et al., Life Sci 2008 (Disease Models, Animal...) : LPS induced PARP activation in circulating lymphocytes was measured by flow cytometry, tumor necrosis factor alpha (TNF-alpha) production was measured by ELISA ... We demonstrate that insulin treatment blocks LPS induced PARP activation in vivo
Mittal et al., Mol Cell Biochem 2011 (Respiratory Distress Syndrome, Adult) : Surfactant also inhibited the LPS induced PARP activation
Liu et al., Hum Immunol 2012 (Inflammation...) : Immunoprecipitation assays showed that LPS stimulation enhanced the binding of PARP-1 with p65 ( RelA ) and poly ( ADP-ribosyl ) ation of p65, which might account for the upregulated transcription activity of nuclear factor ( NF ) -?B and the increased expression of proinflammatory genes
Martinez-Zamudio et al., Mol Cell Biol 2012 : Here we show that through an intracellular signaling pathway, lipopolysaccharide (LPS) stimulation induces PARP-1 enzymatic activity and the ADP-ribosylation of histones at transcriptionally active and accessible chromatin regions in macrophages
Peng et al., Acta Biochim Biophys Sin (Shanghai) 2012 (Inflammation) : Compared with the control, LPS stimulation increased the protein expression of TLR4 and PARP1 ... TLR4 inhibition reduced LPS induced upregulation of inducible nitric oxide synthase (iNOS) and ICAM-1 as well as PARP1