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BCL3 — IL4

Text-mined interactions from Literome

Rebollo et al., Mol Cell Biol 2000 : Cell death is associated with Bcl-3 downregulation and Bcl-3 expression blocks IL-4 deprivation induced apoptosis, suggesting that Bcl-3 acts as a survival factor in the absence of growth factor ... To characterize the IL-4 induced regulation of murine Bcl-3 expression, we cloned the promoter of this gene ... Retardation gels showed that IL-4 specifically induces AP1 and AP1-like binding activity and that mutation of these binding sites abolishes the IL-4 induced Bcl-3 promoter activity, suggesting that these transcription factors are important in Bcl-3 promoter transactivation
Rebollo et al., J Immunol 2001 : IL-4 does not promote translocation of Aiolos or Bcl-xL , but induces tyrosine phosphorylation of Aiolos, which is required for dissociation from Bcl-xL
Wurster et al., J Biol Chem 2002 : We show that expression of the Bcl-2 family member, Bcl-xL , is induced maximally by IL-4 and anti-IgM/IL-4 in a Stat6 dependent manner
Brocke-Heidrich et al., Oncogene 2006 (Multiple Myeloma) : In this study, interleukin (IL)-6 induced BCL3 expression and its effect on survival of multiple myeloma ( MM ) cells were examined
Rautajoki et al., Mol Cell Proteomics 2007 : We demonstrated that IL-4 decreases expression of Fas receptor and increases expression of Bid, Bcl-2, and Bcl-xL
Burton et al., Mucosal Immunol 2013 : IL-4 induces Bcl-2 and Bcl-XL and enhances survival and stimulates proliferation in cultured bone marrow derived mast cells ( BMMC )