Gene interactions and pathways from curated databases and text-mining

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MMP2 — RBBP4

Text-mined interactions from Literome

Liu et al., Cancer Res 2003 (Lung Neoplasms...) : In this study, we test the possibility that HDAC inhibitor may increase RECK expression to inhibit MMP activation and cancer cell invasion ... To explore whether HDAC inhibitor induced inhibition of MMP-2 activation is indeed mediated via RECK, we used small interference RNA ( siRNA ) to block RECK expression and found that inhibition of RECK by siRNA abolished the inhibitory effect of TSA on MMP-2 activation
Wang et al., J Cereb Blood Flow Metab 2011 (Brain Edema...) : Our findings suggest that BBB protection by VPA involves HDAC inhibition mediated suppression of NF-?B activation, MMP-9 induction, and tight junction degradation