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P2RY12 — PI3

Text-mined interactions from Literome

Lova et al., J Biol Chem 2003 (Second Messenger Systems) : Two unrelated inhibitors of phosphatidylinositol 3-kinase (PI3K) , wortmannin and LY294002, totally prevented Rap1B activation in platelets stimulated by cross linking of FcgammaRIIA, by stimulation of the P2Y(12) receptor for ADP, or by epinephrine
Soulet et al., Journal of thrombosis and haemostasis : JTH 2004 (MAP Kinase Signaling System) : The P2Y12 mediated stimulation of proliferation required the pertussis toxin-sensitive activation of PI3-kinase/Akt upstream of MAP-kinases