Gene interactions and pathways from curated databases and text-mining

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EGF — TG

Text-mined interactions from Literome

Pohl et al., Exp Cell Res 1992 : This contrasted strongly with the effects of TSH, EGF , and TPA on the expression of the thyroglobulin gene, a prominent marker of thyroid cell differentiation : in this case, the regulation was much tighter ( high range of stimulation by TSH, strong inhibition by EGF, and suppression of Tg gene expression by TPA ) and displayed a great variability of the level of individual cellular response
Tseng et al., J Clin Endocrinol Metab 1989 (Goiter) : Effects of epidermal growth factor on thyroglobulin and adenosine 3',5'-monophosphate production by cultured human thyrocytes
Roger et al., Eur J Biochem 1985 : Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells