Gene interactions and pathways from curated databases and text-mining

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EGFR — PDK1

Text-mined interactions from Literome

Roztocil et al., Surgery 2009 : Inhibiting the generation of reactive oxygen species with N-acetylcysteine and of epidermal growth factor receptor with AG1478 inhibited PDK1 activation in response to S-1-P ... PDK1 activation requires G beta gamma dependent generation of reactive oxygen species and epidermal growth factor receptor activation
Bhola et al., Mol Cancer Ther 2012 (Carcinoma, Squamous Cell...) : PDK1 contributed to both GPCR induced EGFR activation and cell growth