Gene interactions and pathways from curated databases and text-mining

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DEFB114 — IL6

Text-mined interactions from Literome

Semple et al., Eur J Immunol 2010 (Endotoxemia...) : In addition, in the presence of LPS, hBD3 and the murine orthologue Defb14 ( but not hBD2 ), effectively inhibit TNF-alpha and IL-6 accumulation implying an anti-inflammatory function
Harvey et al., Scientific reports 2013 : In murine JAWSII dendritic cells, DEFB103 significantly attenuated , yet rarely enhanced, the Cxcl2, Il6 , and Csf3 responses to HagB ; and in C57/BL6 mice, DEFB103 significantly enhanced, yet rarely attenuated, the Cxcl1, Csf1, and Csf3 responses