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Zeniou-Meyer et al., Proc Natl Acad Sci U S A 2008
(Coffin-Lowry Syndrome) :
RSK2 physically interacts with and stimulates PLD activity through the phosphorylation of Thr-147 in the PLD1 amino-terminal phox homology domain
Zeniou-Meyer et al., Cell Mol Neurobiol 2010
(Coffin-Lowry Syndrome) :
These results provide the first molecular evidence that RSK2 could regulate neurotransmitter release by activating PLD production of lipids required for exocytosis