◀ Back to TNF
HLA-A — TNF
Text-mined interactions from Literome
Zheng et al., J Immunol 2000
:
Transduced Bcl-2 did not reduce
TNF mediated NF-kappaB activation or constitutive expression of
class I MHC molecules
Willemsen et al., J Immunol 2005
(Melanoma) :
Human scFv-G8 ( POS ) T lymphocytes comprising the gamma + CD28 vs the gamma signaling element alone produced substantially more IL-2,
TNF-alpha , and IFN-gamma in
response to
HLA-A1/MAGE-A1 ( POS ) melanoma cells
Doukas et al., J Immunol 1990
:
TNF but not IL-1 also
increases class I MHC Ag expression
Hinrichs et al., Mol Immunol 2009
:
Stimulation with IFN-gamma and/or
TNF-alpha led to an increase of HLA-A*3014L secretion to a detectable level and
increased HLA-A*3001 expression up to 8-fold, but did not show any difference in the increase of mRNA levels between HLA-A*3014L and A*3001
Leszczynski et al., Am J Pathol 1990
:
Finally,
TNF alpha induced
class I MHC expression was inhibited strongly by IL-1 alpha
Pfizenmaier et al., J Immunol 1987
(Neoplasms) :
Tumor necrosis factor enhances
HLA-A , B,C and HLA-DR gene expression in human tumor cells
Yoshioka et al., Liver 1989
:
These findings suggest that IFN alpha, IFN gamma, and
TNF alpha may
play similar roles in enhancement of
HLA-A , B, C expression of hepatocytes in hepatitis and hepatoma cells
Pober et al., Ciba Found Symp 1987
(Inflammation) :
Coincident with morphological change,
TNF and LT ( but not IL-1 alpha or IL-1 beta )
cause a marked increase in
HLA-A , B mRNA and antigen expression
Stephens et al., J Autoimmun 1997
(Diabetes Mellitus, Type 1) :
In the current study we have examined the effect of the same inhibitor of NF-kappaB on class I major histocompatibility complex ( MHC ) protein expression in NIT-1 cells and shown that inhibition of NF-kappaB activation decreased basal and
TNF induced
class I MHC levels