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GSTP1 — MBD2
Text-mined interactions from Literome
Bakker et al., J Biol Chem 2002
(Carcinoma, Hepatocellular) :
To test whether
MBD2 might be
responsible for the inhibition of
GSTP1 transcription from hypermethylated GSTP1 promoters, siRNAs were used to reduce MBD2 polypeptide levels in Hep3B cells
Lin et al., Cancer Res 2003
(Breast Neoplasms) :
We report here thathypermethylation of CpG dinucleotides at the 5 ' transcriptional regulatory region was sufficient to
inhibit GSTP1 transcription in MCF-7 breast cancer cells and that repression of GSTP1 transcription was mediated in part by the methyl-CpG binding domain ( MBD ) protein
MBD2