Gene interactions and pathways from curated databases and text-mining

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CCND1 — HDAC2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Zhang et al., Mol Cell Biol 2002 (Rhabdoid Tumor) : In addition, INI1/hSNF5 repressed transcription of cyclin D1 gene in MON, in a histone deacetylase (HDAC) dependent manner
Yamaguchi et al., J Biol Chem 2005 : HDAC inhibitors suppressed the induction of both cyclin D1 and collagenase-1 transcription by inhibiting the binding of c-Jun to the respective promoters
Findeisen et al., Arterioscler Thromb Vasc Biol 2011 (Disease Models, Animal...) : Furthermore, HDAC inhibition repressed mitogen induced cyclin D1 mRNA expression and cyclin D1 promoter activity
Jeong et al., Biochem Biophys Res Commun 2013 (Colorectal Neoplasms) : These findings suggest that cell growth inhibition and apoptosis by PCA may be a result of HDAC2 mediated cyclin D1 suppression