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FGF2 — ODC1

Text-mined interactions from Literome

Hardin et al., J Cell Biochem 2002 (Cell Transformation, Neoplastic) : Increased ornithine decarboxylase (ODC) expression was found to occur in both types of bFGF transfected cells suggesting that altered ODC expression in response to bFGF stimulation may occur through both autocrine and intracrine mechanisms
Sarfati et al., Pancreas 1992 (Pancreatic Neoplasms) : Our aim was to study the effect of bFGF on ODC activity and ODC mRNA expression in a pancreatic tumoral cell line, AR4-2J ... To elucidate the mechanism by which bFGF stimulates ODC activity, we measured the ODC mRNA levels by Northern blot hybridization using a 32P labeled rat cDNA probe
Damon et al., Exp Cell Res 1992 : One milligram per milliliter of heparin, a concentration that inhibited bFGF induced neurite outgrowth, also inhibited bFGF induced increases in S6 phosphorylation and ODC activity
Damon et al., J Cell Biol 1990 (Adrenal Gland Neoplasms...) : In a PC12 cell mutant that is deficient in cAMP responsiveness ( A126-1B2 ), all three growth factors maximally induced the transcription of d5 and neurite outgrowth, but aFGF and bFGF did not induce significant increases in ODC ... These observations lead us to conclude that ( a ) cAMP- and PKC dependent events are, at least in part, causally linked to NGF, aFGF, and bFGF induction of both ODC and transcription of d2 and may control functionally redundant pathways ; ( b ) NGF, aFGF, and bFGF can elicit neurite outgrowth and increase transcription of d2 and d5 in PC12 cells via mechanisms that are independent of both PKC and cAMP ; ( c ) NGF, aFGF, and bFGF can induce ODC in the absence of PKC ; and ( d ) aFGF and bFGF require cAMP responsiveness to induce ODC in PC12 cells
Morrison et al., Cardiovasc Res 1995 : Basic fibroblast growth factor also stimulated ODC activity in a dose dependent manner with levels approximating the maximum obtainable with FBS
Scalabrino et al., Lab Invest 1995 (Nerve Degeneration...) : Basic fibroblast growth factor induced SC ODC only in TGX-rats