Gene interactions and pathways from curated databases and text-mining

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CERS6 — SMPD2

Text-mined interactions from Literome

Lee et al., J Biol Chem 2000 : Fumonisin B ( 1 ), an inhibitor of ceramide synthase , and glutathione, an inhibitor of neutral sphingomyelinase , both reversed the effect of TNF-alpha on PKC alpha activity, suggesting that ceramide production is necessary for the action of TNF-alpha
Suzuki et al., Int J Oncol 2003 : The enhancement of Fas induced apoptosis by pre-treatment with neuraminidase was inhibited by z-VAD-fmk, a broad caspase inhibitor, and Ac-LEHD-CHO, an inhibitor of caspase-9, but not by Ac-IETD-CHO an inhibitor of caspase-8 or 6, imipramine, an inhibitor of acidic sphingomyelinase, glutathione, an inhibitor of neutral sphingomyelinase and Fumonisin B1, an inhibitor of ceramide synthase