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ARSK — HSPB1

Text-mined interactions from Literome

Stetler et al., J Neurosci 2008 (Brain Infarction...) : While Hsp27 overexpression did not suppress activation of an upstream regulatory kinase of the MKK/JNK cascade, ASK1, Hsp27 effectively inhibited ASK1 activity via a physical association through its N-terminal domain and the kinase domain of ASK1
Stetler et al., J Neurosci 2012 (Anoxia...) : Together, these data demonstrate that HSP27 requires PKD mediated phosphorylation for its suppression of ASK1 cell death signaling and neuroprotection against ischemic injury