Gene interactions and pathways from curated databases and text-mining

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HRAS — MMP3

Text-mined interactions from Literome

Kang et al., Oncol Rep 2009 (Breast Neoplasms...) : Taken together, this study clearly demonstrated the inhibitory effect of simvastatin and lovastatin on H-Ras induced invasion, MMP expression and signal transduction in MCF10A breast epithelial cells, providing supporting rationale for future statin trials as a therapeutic intervention to regulate breast cancer metastasis
de Launay et al., Am J Pathol 2010 (Arthritis, Experimental...) : Constitutively active mutants of each Ras protein enhanced IL-1ß induced FLS matrix metalloproteinase-3 production, while only active H-Ras enhanced IL-8 production
Liao et al., Mol Med 2012 (Neoplasm Metastasis...) : CSE1L overexpression also triggered microvesicle generation, and CSE1L knockdown diminished v-H-Ras induced microvesicle generation, matrix metalloproteinase (MMP)-2 and MMP-9 secretion and metastasis of B16F10 melanoma cells