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HLA-G — IL10
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Steck et al., Zentralbl Gynakol 2002
:
The suppressive
effect of
HLA-G and HLA-E on the secretion of TNF-alpha ( Th1 cytokine ),
IL-10 ( Th2 cytokine ) and IL-8 ( chemokine ) by immature DC could be interpreted as further evidence for the central immunotolerance role of HLA-G and HLA-E during early pregnancy
Rizzo et al., J Allergy Clin Immunol 2005
(Asthma) :
The study was designed to investigate whether this impaired
IL-10 production can
affect the expression and the secretion of soluble
HLA-G ( sHLA-G ) -1/HLA-G5 molecules
Selmani et al., Stem Cells 2008
:
Our data show that MSCs secrete the soluble isoform
HLA-G5 and that such secretion is
interleukin-10 dependent
Blanco et al., Hum Reprod 2008
:
Interleukin (IL)-10 , a cytokine associated with normal pregnancy,
increased the expression of
HLA-G by DSC ( P < 0.00001 ), whereas IL-2, a cytokine involved in spontaneous abortion, showed no effect
Monsiváis-Urenda et al., J Clin Immunol 2011
(Lupus Erythematosus, Systemic) :
In addition, monocytes from SLE patients showed a diminished induction of
HLA-G expression in
response to stimulation with
IL-10
Zhao et al., PloS one 2013
:
To analyze the
effects of
IL-10 on the
HLA-G expression and the apoptosis of trophoblasts infected with Toxoplasma gondii ...
IL-10 regulates
HLA-G expression in T. gondii infected trophoblasts