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CCL2 — PHKA2

Text-mined interactions from Literome

Vitale et al., J Immunol 2004 : We demonstrated that s-FKN abrogates the MCP-1 induced SAPK2/p38 activation as well as the upstream Pyk2 activity
Hu et al., J Immunol 2008 (MAP Kinase Signaling System) : IFN-gamma altered monocyte responses to CCL2 by modulating the activity of Pyk2 , JNK, and the GTPases Rac and Cdc42, and inhibiting CCL2 induced activation of the downstream p21 activated kinase that regulates the cytoskeleton and cell polarization
Anand et al., Mol Immunol 2009 (MAP Kinase Signaling System...) : Inhibition of Pyk2 activity using a pharmacological inhibitor, Tyrphostin A9 significantly attenuated LPS induced Pyk2 tyrosine phosphorylation, p38 MAP kinase ( MAPK ) activation, NF-kappaB activation, and MCP-1 expression