◀ Back to HIF1A

ANGPT4 — HIF1A

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: ANGPT4 → HIF1A (increases, ANGPT4 Activity) Yamakawa et al., Circ Res 2003*
  Evidence: In primary human endothelial cells, hypoxia, desferrioxamine, or infection with Ad2/HIF-1alpha/VP16, an adenoviral vector encoding a constitutively stable hybrid form of HIF-1alpha, increased the mRNA and protein levels of VEGF, angiopoietin-2 (Ang-2), and angiopoietin-4 (Ang-4)
• OpenBEL Selventa BEL large corpus: ANGPT4 → HIF1A (increases, ANGPT4 Activity) Yamakawa et al., Circ Res 2003*
  Evidence: Ang-4 was also induced by hypoxia or Ad2/HIF-1alpha/VP16 in human cardiac cells

Text-mined interactions from Literome

Yamakawa et al., Circ Res 2003 : Ang-4 was also induced by hypoxia or Ad2/HIF-1alpha/VP16 in human cardiac cells, whereas Ang-1 expression remained unchanged
Yamakawa et al., American journal of physiology. Renal physiology 2004 (Adenocarcinoma, Clear Cell...) : In RPTE cells, angiopoietin-4 (Ang-4) expression was selectively induced by hypoxia or by expression of a hybrid form of HIF-1alpha
Abaci et al., Am J Physiol Cell Physiol 2010 : Corresponding upregulation of VEGF, ANGPT2 , and GLUT-1 was observed in response to HIF-1alpha accumulation, whereas upregulation of ANGPT1 was detected only in hESCs and iPSCs