Gene interactions and pathways from curated databases and text-mining

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DDT — JUN

Text-mined interactions from Literome

Frigo et al., Environ Health Perspect 2002 : Our results demonstrate that DDT and dichlorodiphenyldichloroethane ( DDD ) were the most potent activators of AP-1 activity ; 2,2-bis ( p-chlorophenyl ) acetic acid failed to activate ... In addition, DDT , DDD, and dichlorodiphenyldichloroethylene ( DDE ) could also stimulate AP-1 activity in the estrogen-unresponsive human embryonic kidney 293 cells using a different promoter context
Han et al., Toxicol Appl Pharmacol 2008 : Phosphatidylinositol 3 (PI3)-kinase, its downstream signaling molecule, Akt, and mitogen activated protein kinases ( MAPK ) were also significantly activated by the o, p'-DDT induced AP-1 and CRE activation