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MMP9 — PGF
Text-mined interactions from Literome
Ulug et al., Mol Hum Reprod 2001
:
PGF ( 2alpha )
caused a 2.4- and 1.9-fold increase in the production of MMP-2 and
MMP-9 in the decidua, respectively ( P < 0.05 ), and an 11.3-fold increase of the active form of MMP-2 ( 62 kDa ) which could hardly be detected in basal culture conditions ( P < 0.01 ) ... The production of MMP-2 and
MMP-9 and TIMP-1 by the amniotic and chorionic membranes was not
affected by
PGF ( 2alpha )
Ricke et al., Biol Reprod 2002
:
The objectives of these experiments were to determine whether 1 ) PGF ( 2 alpha ) affects expression of mRNA encoding fibrillar collagenases ( MMP-1 and -13 ), gelatinases A and B ( MMP-2 and -9 ), membrane type (mt)-1 MMP ( MMP-14 ), stromelysin ( MMP-3 ), and matrilysin ( MMP-7 ), and 2 )
PGF ( 2 alpha )
increases MMP activity during PGF ( 2 alpha ) -induced luteolysis in sheep ...
MMP activity was localized ( in situ zymography ) to the pericellular area of various cell types in the 0-h group and was markedly
increased by 30 min
post-PGF ( 2 alpha )
Rafii et al., Ann N Y Acad Sci 2003
:
The late phase of hematopoietic recovery was driven by
PlGF induced upregulation of
matrix metalloproteinase-9 (MMP-9) in the BM, mediating the release of soluble Kit-ligand ( sKitL )
Lappas et al., Mol Hum Reprod 2012
:
PLGF significantly
increased interleukin (IL)-6 and IL-8 gene expression and secretion, cyclooxygenase-2 expression and resultant prostaglandin ( PG ) E ( 2 ) and PGF ( 2a ) release, and
MMP-9 gene expression and enzyme production