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ASPN — TGFB1

Text-mined interactions from Literome

Kou et al., J Biol Chem 2007 (Osteoarthritis) : TGF-beta1 induced endogenous ASPN mRNA expression over time in vitro, and this induction was suppressed by the TGF-beta type I receptor kinase inhibitor SB431542 ... Inhibition of Smad3 significantly reduced TGF-beta1 induced ASPN expression, whereas overexpression of Smad3 augmented the induction ... Our findings indicate that TGF-beta1 induces ASPN through Smad3 but that this induction is indirect
Kou et al., J Bone Miner Metab 2010 : In contrast with previous in vivo findings, asporin did not affect the interaction between TGF-beta1 and the TGF-beta type II receptor ( TbetaRII ) by itself or in the presence of type II collagen in vitro
Turtoi et al., J Proteome Res 2011 (Carcinoma, Pancreatic Ductal...) : Of these, transforming growth factor beta induced ( TGFBI ), latent transforming growth factor beta binding 2 ( LTBP2 ), and asporin (ASPN) were further investigated by employing large scale immunohistochemistry based validations