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MAPK7 — NR4A1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Kovalovsky et al., Mol Endocrinol 2002
(MAP Kinase Signaling System) :
The
MAPK kinase inhibitors did not
affect Nur77 and Nurr1 mRNA induction but blocked CRH or cAMP stimulated Nur transcriptional activity
Fujii et al., Genes Cells 2008
:
Here we demonstrate that the
MAPK induced phosphorylation of
Nur77 during T cell activation plays a critical role in the induction of apoptosis
Huang et al., Neurosci Lett 2008
(Brain Infarction...) :
The induction of c-fos, c-jun,
nur77 , and zif268 by hypoxia was
inhibited by naloxone ( 0.1 microM ) and
MAPK inhibitors ( 10 microM of U0126, D98059, SB203580 )
Shao et al., J Mol Cell Cardiol 2010
(Inflammation) :
OxLDL activated the phosphorylation ERK1/2 and p38 MAPK, inhibition of p38
MAPK but not ERK1/2
attenuated Nur77 expression