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ARG1 — IL13

Text-mined interactions from Literome

Chang et al., J Immunol 2000 : The involvement of tyrosine kinases, cyclic AMP/protein kinase A, and p38 mitogen activated protein kinase in IL-13 mediated arginase I induction in macrophages : its implications in IL-13 inhibited nitric oxide production ... The signaling molecules involved in IL-13 induced arginase activation were also determined
Witte et al., J Surg Res 2002 : The effect of transforming growth factor beta1 ( TGF-beta1 ), interleukin-4 (IL-4), lipopolysaccharide, and wound fluid on arginase activity was also investigated
Zimmermann et al., J Clin Invest 2003 (Asthma...) : Lung arginase activity and mRNA expression were strongly induced by IL-4 and IL-13 , and were differentially dependent on signal transducer and activator of transcription 6
Lindemann et al., Naunyn Schmiedebergs Arch Pharmacol 2003 : Glucocorticoid inhibition of interleukin-4 (IL-4) and interleukin-13 (IL-13) induced up-regulation of arginase in rat airway fibroblasts ... In conclusion, IL-4 and IL-13 can cause a marked up-regulation of arginase activity in rat airway fibroblasts and these effects can be inhibited by glucocorticoids
Madhankumar et al., Neoplasia (New York, N.Y.) 2004 (Glioma) : We observed that Lys-105 and Arg-109 are critical for IL13 binding to IL13Ralpha2, indeed
Barksdale et al., Surgery 2004 : Although isoproterenol, IL-4, IL-10, and IL-13 individually induced arginase , significant synergy between the combination of isoproterenol with either TGF-beta or the TH2 cytokines was observed
Yang et al., J Immunol 2006 (Asthma...) : In the present study, we show that arginase I expression is also regulated in the lung in a STAT6 dependent manner by Th2 induced allergic inflammation or by IL-13 alone ... IL-13 induced expression of arginase I correlated directly with increased synthesis of urea and with reduced synthesis of NO
Lotz et al., Immunology 2007 : Also, IL-4 or IL-13 led to rapid signal transducer and activator of transcription 6 phosphorylation, diminished inducible NO synthase expression, and enhanced the antagonistic arginase 1 activity
Ueta et al., Invest Ophthalmol Vis Sci 2008 (Conjunctivitis...) : Because Arg110Gln affects serum IL-13 , plasma IL-13 levels were also examined
Highfill et al., Blood 2010 (Graft vs Host Disease) : Exogenous IL-13 produced an MDSC subset ( MDSC-IL-13 ) that was more potently suppressive and resulted in arginase-1 up-regulation
Corraliza et al., Biochim Biophys Acta 1997 : Moreover, interleukin 10 which induces arginase in macrophages is able to increase the cAMP dependent protein kinase A activity