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GDI2 — RAB3A

Text-mined interactions from Literome

Chen et al., J Biol Chem 2013 (Neurodegenerative Diseases) : Accumulation of membrane bound a-synuclein was induced by the expression of a GTPase-deficient Rab3a mutant, by a dominant negative GDP dissociation inhibitor mutant unable to recycle Rab3a off membranes, and by Hsp90 inhibitors, radicicol and geldanamycin, which are known to inhibit Rab3a dissociation from membranes ... Our results suggest that membrane bound GTP-Rab3a stabilizes a-synuclein on synaptic vesicles and that the GDP dissociation inhibitor·Hsp90 complex that controls Rab3a membrane dissociation also regulates a-synuclein dissociation during synaptic activity
Miyazaki et al., FEBS Lett 1994 : Moreover, Rab GDI slightly inhibits the Rab3A GRF effect on the lipid unmodified form of Rab3A , but does not affect the MSS4 effect on the lipid unmodified form of Rab3A