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ADAM17 — TNFRSF1A
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Pradillo et al., J Cereb Blood Flow Metab 2005
(Brain Ischemia) :
In summary, these data show that IPC produces neuronal upregulation of
TACE and TNFR1, and that the pathway
TACE/TNF-alpha/TNFR1/NF-kappaB is
involved in IT
Canault et al., Am J Pathol 2007
(Atherosclerosis) :
We sought to examine whether
TACE/ADAM17 is present on human plaque MPs and whether these MPs would
affect TNF and
TNFR-1 cellular shedding
D'Alessio et al., J Cell Mol Med 2012
:
The purpose of this study was to determine the role of these domains in
TACE mediated
TNFR1 shedding in response to histamine
McMahan et al., Am J Physiol Gastrointest Liver Physiol 2013
(Inflammation) :
We conclude that
ADAM17 regulates TNF,
TNFR1 , and AR in the liver, and its expression in both hepatocytes and myeloid cells is important for TNF regulation after LPS injury or 2/3 PH, but is not required for liver regeneration