Gene interactions and pathways from curated databases and text-mining

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CREB3 — PTEN

Text-mined interactions from Literome

Hong et al., J Pharmacol Exp Ther 2003 : Thus, our results for the first time provide evidence that cilostazol prevents TNF-alpha induced cell death by suppression of PTEN phosphorylation and activation of Akt/CREB phosphorylation via mediation of the maxi-K channel opening
Gu et al., Cancer Res 2011 : In this report, we demonstrate the transcription factor cyclic AMP response element binding protein ( CREB ) is a protein target of PTEN phosphatase and that PTEN deficiency leads to CREB phosphorylation independent of the PI3K/AKT pathway