Gene interactions and pathways from curated databases and text-mining

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ACO1 — IFNG

Text-mined interactions from Literome

Kim et al., J Biol Chem 2000 : In this study, we demonstrated that stimulation of RAW 264.7 cells with lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) increased IRP-1 binding activity, whereas RNA binding of IRP-2 decreased and was followed by a degradation of this protein
Kim et al., Biometals 2003 : Moreover, we demonstrated that stimulation of RAW 264.7 cells with lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) increased IRP1 binding activity, whereas RNA binding of IRP2 decreased and was followed by a degradation of this protein
Recalcati et al., Blood 1998 : In the present study, we showed that stimulation of murine macrophage J774 cells with interferon (IFN)-gamma/lipopolysaccharide (LPS) resulted in a nitric oxide dependent modulation of the activity of iron regulatory proteins (IRP)-1 and 2, cytoplasmic proteins which, binding to RNA motifs called iron responsive elements ( IRE ), control ferritin translation