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MMP2 — PRDX2
Text-mined interactions from Literome
Ailenberg et al., Biochem Biophys Res Commun 2002
:
Furthermore,
TSA inhibits cytochalasin D-induced activation of
gelatinase A , but TSA does not affect other members of the gelatinase A activation complex, MT1-MMP and TIMP-2 ... This finding not only strengthens the rationale for continuing to investigate the therapeutic utility of TSA in cancer, but also, provides evidence that
TSA inhibition of
gelatinase A expression and activation can be used as a biological marker to monitor and determine end-points of clinical trials involving TSA
Liu et al., Cancer Res 2003
(Lung Neoplasms...) :
Moreover, up-regulation of RECK expression by
TSA attenuated
MMP-2 activity
Ma et al., Chin J Cancer 2009
(Neoplasm Invasiveness...) :
TSA and ROZ in combination
reduced MMP-2 expression more obviously than ROZ alone
Crosson et al., Invest Ophthalmol Vis Sci 2010
(Reperfusion Injury...) :
Western blot and immunohistochemical analyses were used to evaluate
TSA induced changes in histone-H3 acetylation and
MMP secretion
Jeon et al., Mol Cancer Ther 2010
(Neoplasm Invasiveness...) :
TSA suppressed the activity of
matrix metalloproteinase-2 (MMP-2) and MMP-9, induced by hypoxia, and significantly inhibited hypoxia stimulated migration and invasion of both cancer cells
Culley et al., Arthritis Rheum 2013
(Disease Models, Animal...) :
All of the HDAC inhibitors prevented degradation of BNC, in which
TSA and MS-275
repressed cytokine induced
MMP expression