Gene interactions and pathways from curated databases and text-mining

◀ Back to PRDX2

MMP2 — PRDX2

Text-mined interactions from Literome

Ailenberg et al., Biochem Biophys Res Commun 2002 : Furthermore, TSA inhibits cytochalasin D-induced activation of gelatinase A , but TSA does not affect other members of the gelatinase A activation complex, MT1-MMP and TIMP-2 ... This finding not only strengthens the rationale for continuing to investigate the therapeutic utility of TSA in cancer, but also, provides evidence that TSA inhibition of gelatinase A expression and activation can be used as a biological marker to monitor and determine end-points of clinical trials involving TSA
Liu et al., Cancer Res 2003 (Lung Neoplasms...) : Moreover, up-regulation of RECK expression by TSA attenuated MMP-2 activity
Ma et al., Chin J Cancer 2009 (Neoplasm Invasiveness...) : TSA and ROZ in combination reduced MMP-2 expression more obviously than ROZ alone
Crosson et al., Invest Ophthalmol Vis Sci 2010 (Reperfusion Injury...) : Western blot and immunohistochemical analyses were used to evaluate TSA induced changes in histone-H3 acetylation and MMP secretion
Jeon et al., Mol Cancer Ther 2010 (Neoplasm Invasiveness...) : TSA suppressed the activity of matrix metalloproteinase-2 (MMP-2) and MMP-9, induced by hypoxia, and significantly inhibited hypoxia stimulated migration and invasion of both cancer cells
Culley et al., Arthritis Rheum 2013 (Disease Models, Animal...) : All of the HDAC inhibitors prevented degradation of BNC, in which TSA and MS-275 repressed cytokine induced MMP expression