Gene interactions and pathways from curated databases and text-mining

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PAF1 — SRI

Text-mined interactions from Literome

Dunoyer-Geindre et al., Allergy 1992 (Drug Hypersensitivity) : The aggregating power was abolished by using SRI 63-441 ( Sandoz ), a PAF acether inhibitor
Dobrowsky et al., Am J Physiol 1991 : Effect of SRI 63-675 on hemodynamics and blood PAF levels during porcine endotoxemia
Parks et al., Biol Reprod 1990 : Platelet activation by purified PAF and by sperm phospholipid fractions was inhibited by the receptor antagonist SRI 63-675
Ryan et al., J Reprod Fertil 1990 : The specificity of action of PAF was confirmed by the absence of any effect on the oxidative metabolism of glucose by lyso-PAF ( a catabolite of PAF ) over a concentration range of 0.0202-20.2 microM and by the demonstration that SRI 63-441 ( a PAF-receptor antagonist ) significantly reduced the amount of CO2 produced from glucose in response to 9.3 microM-PAF and abolished the effect on lactate metabolism in response to 1.86 microM-PAF