Gene interactions and pathways from curated databases and text-mining

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ACP2 — TNFSF11

Text-mined interactions from Literome

Mancini et al., Biochem Biophys Res Commun 2000 (Leukemia, Monocytic, Acute) : We show that OPGL alone and in combination with macrophage colony stimulating factor ( CSF-1 ) dramatically reduced replication and increased tartrate-resistant acid phosphatase activity
Liu et al., J Biol Chem 2003 : Involvement of upstream stimulatory factors 1 and 2 in RANKL induced transcription of tartrate-resistant acid phosphatase gene during osteoclast differentiation
Zhang et al., J Immunol 2003 : Over-expression of SHP-1 ( C453S ) significantly enhanced the number of tartrate-resistant acid phosphatase positive multinuclear osteoclast-like cells in response to RANKL in a dose dependent manner
Shi et al., Gene 2004 : YY1 is involved in RANKL induced transcription of the tartrate-resistant acid phosphatase gene in osteoclast differentiation
Sørensen et al., J Bone Miner Metab 2007 : No expression of osteoclast markers was observed in the absence of RANKL, whereas RANKL dose-dependently induced the expression of cathepsin K, tartrate-resistant acid phosphatase ( TRACP ), and matrix metallo proteinase (MMP)-9
Kim et al., Phytother Res 2009 (Bone Resorption) : ( - ) -Saucerneol significantly inhibited the RANKL induced activity of tartrate-resistance acid phosphatase ( TRAP, an early marker of osteoclast formation ) and formation of osteoclasts in a dose dependent manner
Kim et al., J Cell Physiol 2009 (Bone Resorption) : Therefore, we evaluated the effects of 222 natural compounds on the RANKL induced tartrate-resistance acid phosphatase ( TRAP ; a marker for osteoclast differentiation ) activity and multinucleated osteoclast formation in RAW264.7 murine macrophage cells
Mazière et al., J Cell Physiol 2009 (Bone Resorption) : OxLDL, within the range of 10-50 microg protein/ml, prevented RANKL induced generation of multinucleated osteoclast-like cells and RANKL induced tartrate resistant acid phosphatase ( TRAP ) activity
Hasegawa et al., Biol Pharm Bull 2010 (Bone Resorption) : Honokiol markedly inhibited RANKL induced tartrate-resistant acid phosphatase ( TRAP ) activity and the formation of TRAP positive multinucleated cells in both bone marrow derived monocytes and RAW264 cells
Okayasu et al., J Biol Chem 2012 (Bone Resorption...) : Despite these findings, RANK signaling, including the activation of Erk and Akt, was normal in LDLR ( -/- ) preosteoclasts, and RANKL induced expression of NFATc1 ( a master regulator of osteoclastogenesis ), cathepsin K, and tartrate-resistant acid phosphatase was equivalent in LDLR-null and wild-type cells
Shim et al., Pharmacognosy magazine 2012 : ST-WE significantly inhibited RANKL induced tartrate-resistant acid phosphatase ( TRAP ) activity and formation of multinucleated osteoclasts in RAW264.7 cells