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IRF6 — TIMP1
Text-mined interactions from Literome
Lim et al., Am J Respir Crit Care Med 2000
(Pulmonary Emphysema) :
Airway macrophages from smokers released greater amounts of MMP-9 and
TIMP-1 at baseline and in
response to IL-1beta and
LPS than did those of nonsmokers
Corbel et al., Eur J Pharmacol 2001
(Acute Disease...) :
The increase in tissue inhibitor of matrix metalloproteinase (
TIMP ) -1
induced by
LPS was not modified by the two drugs
Smith et al., Br J Ophthalmol 2004
:
IL-1alpha and
LPS had no effect on
MMP/TIMP production by cultured corneal epithelial cells and keratocytes
Li et al., Biol Reprod 2007
:
There was no
effect of
LPS on
TIMP1
Hyc et al., Int J Mol Med 2011
:
LPS increased the mRNA levels of IL-6, IL-1ß, TGF-ß1, MMP1a, MMP1b, MMP3, MMP9, MMP13, MMP14,
TIMP1 and TIMP3 while the mRNA levels of MMP2, TIMP2 and TIMP4 were significantly decreased
Lew et al., PloS one 2013
(Fibrosis) :
LPS increased LV expression of collagen Ia1, collagen IIIa1, MMP2, MMP9,
TIMP1 , periostin and IL-6 ( P < 0.05 moderate vs low dose LPS and vs control )
Zhang et al., J Immunol 1998
:
The PGE2 independent induction of monocyte MMP-9 and TIMP-1 by these cytokines differed from
stimulation of MMP-9 and
TIMP-1 by
LPS , which is in large part PG-dependent
Nothnick et al., Am J Reprod Immunol 1998
(Endometriosis) :
LPS induced a dose dependent increase ( P < 0.05 ) in
TIMP-1 mRNA expression at levels of 1 microgram ( 70.0 % +/- 5.8 % greater than the control ), 10 micrograms ( 83.0 % +/- 12.0 % greater than the control ), and 25 micrograms ( 100.0 % +/- 10.0 % greater than the control )