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BCL6 — IL11
Text-mined interactions from Literome
He et al., J Clin Invest 2005
(Lung Diseases...) :
In contrast,
IL-11 stimulated A1, diminished the toxic effects of hyperoxia,
stimulated Bcl-2 and
Bcl-xl , and enhanced murine survival in 100 % O ( 2 ) ... In A1-null mice,
IL-11 induced protection, survival advantage, and Bcl-2 and
Bcl-xl induction were significantly decreased
Nakayamada et al., Immunity 2011
:
Herein, we showed
interleukin-12 acting via the transcription factor STAT4
induced both Il21 and
Bcl6 genes, generating cells with features of both Tfh and Th1 cells