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ATP5O — IL1B

Text-mined interactions from Literome

Kreydiyyeh et al., J Interferon Cytokine Res 2002 : Interleukin-1beta increases urine flow rate and inhibits protein expression of Na ( + ) /K ( + ) -ATPase in the rat jejunum and kidney ... The effect of interleukin-1beta (IL-1beta) on urine flow rates and Na ( + ) /K ( + ) -ATPase activity and expression was studied in rat intestinal and renal epithelia ... IL-1beta inhibited , in a dose dependent manner, the activity of Na ( + ) /K ( + ) -ATPase in villus and crypt jejunal cells and in medullary and cortical kidney cells
Al-Sadi et al., Eur Cytokine Netw 2003 : IL-1beta reduced , in these cells also, the activity and expression of ATPase , in a dose and time dependent manner ... Curcumin, a JNK/AP-1 inhibitor, partially abolished the effect of IL-1beta on ATPase expression but did not interfere with the effect of PGE2 ... These results indicate that IL-1beta reduces the expression of ATPase independently of NFkB but, through a major pathway involving p38 and COX-2/PGE2, and another pathway involving JNK/AP1
Ye et al., Am J Physiol Lung Cell Mol Physiol 2004 : Epithelial Na+ channel and Na+-K+-ATPase subunit expressions were both increased by IL-1beta and attenuated by cortisol synthesis inhibition
Kreydiyyeh et al., Pflugers Arch 2004 : The signal transduction pathway that mediates the effect of interleukin-1 beta on the Na+-K+-ATPase in LLC-PK1 cells ... IL-1beta reduces the activity and protein expression of Na ( + ) -K ( + ) -ATPase in rat kidney cells
Kreydiyyeh et al., Cytokine 2004 (MAP Kinase Signaling System) : Interleukin-1 beta inhibits Na+-K+ ATPase activity and protein expression in cardiac myocytes ... IL-1beta inhibited by around 70 % the activity of the ATPase in the left and right ventricles
Nair et al., Am J Physiol Lung Cell Mol Physiol 2005 : Epithelial sodium channel and Na-K-ATPase subunit expressions were both increased by IL-1beta , but not further by oxytocin
Kolkhof et al., Biochem Biophys Res Commun 2010 : We show here that endogenous and plant derived inhibitors of the Na ( + ) /K ( + ) -ATPase , i.e. the cardiac glycosides ouabain and digitoxin, inhibit IL-1beta- and IL-6 induced APP expression in human hepatoma cells and primary human hepatocytes ( PHH ) at nanomolar concentrations
McTiernan et al., Circ Res 1997 : The effects on transcript levels were gene specific ; IL-1 beta induced transcripts for inducible NO synthase (iNOS), did not alter GAPDH transcripts, and reduced sarcoplasmic reticulum Ca ( 2+ ) -ATPase ( 65 % of control, P < .001 ) transcripts
Kreydiyyeh et al., Life Sci 1998 : Studies on the effect of IL-1beta on the activity of the intestinal Na+-K+ ATPase demonstrated a significant inhibition of the pump