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ATP5O — SGK1
Text-mined interactions from Literome
Verrey et al., Ann N Y Acad Sci 2003
:
Short-term aldosterone action on Na,
K-ATPase surface expression :
role of aldosterone induced
SGK1 ?
Alvarez de la Rosa et al., Am J Physiol Cell Physiol 2006
:
SGK1 activates
Na+-K+-ATPase in amphibian renal epithelial cells
Musch et al., Am J Physiol Gastrointest Liver Physiol 2008
:
The second phase involves
SGK dependent increases in total NHE3 and Na ( + ) -K ( + )
-ATPase protein expression and activities
Lang et al., Expert Opin Ther Targets 2009
(Diabetes Mellitus, Type 2) :
SGK1 activates ion channels ( including ENaC, TRPV5, ROMK, KCNE1/KCNQ1 and CLCKa/Barttin ), carriers ( including NCC, NKCC, NHE3, SGLT1 and EAAT3 ), and the Na ( + ) /K ( + )
-ATPase
Lang et al., Expert Opin Ther Pat 2010
:
SGK1 regulates ion channels ( including ENaC, KCNE1/KCNQ1 ), carriers ( including NCC, NHE3, SGLT1 ), Na ( + ) /K ( + )
-ATPase , enzymes ( including glycogen-synthase-kinase-3 ) and transcription factors ( including FOXO3a, ss-catenin, NF-kappaB )
Lang et al., J Nephrol 2010
(Hypertension...) :
SGK1 enhances the activity of a variety of ion channels such as ENaC, TRPV5, ROMK, KCNE1/KCNQ1 and ClCKb ; carriers such as NHE3, NKCC2, NCC and SGLT1 ; as well as the
Na+/K+-ATPase