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CEBPB — MAPK4
Text-mined interactions from Literome
Leu et al., Mol Cell Biol 2003
:
Impaired hepatocyte DNA synthetic response posthepatectomy in insulin-like growth factor binding protein 1-deficient mice with defects in
C/EBP beta and
mitogen activated protein kinase/extracellular signal regulated kinase
regulation
Basak et al., J Biol Chem 2005
(MAP Kinase Signaling System) :
NF-kappaB activation requires the classical TLR4 initiated signaling cascade leading to IkappaB phosphorylation as well as PI-3K/Rac1/p21 activated kinase (PAK) 1 signaling, whereas
C/EBPbeta activation
requires PI-3K/Akt/p38
mitogen activated protein ( MAP ) kinase signaling
Seymour et al., J Biol Chem 2006
:
They identify an essential function of the C/EBPbeta transcription factor in mouse XOR expression and suggest a potential role for p38
MAPK activation of
C/EBPbeta in mammary epithelial cells
Horie et al., Microbes Infect 2007
(HIV Infections) :
TRAF
activation of
C/EBPbeta ( NF-IL6 ) via p38
MAPK induces HIV-1 gene expression in monocytes/macrophages
Patel et al., J Biol Chem 2007
:
These results, confirmed in primary human hepatocytes and CASMC, demonstrate for the first time that IL-17 is a potent inducer of CRP expression via p38
MAPK and ERK1/2 dependent NF-kappaB and
C/EBPbeta activation and suggest that IL-17 may mediate chronic inflammation, atherosclerosis, and thrombosis