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ESR2 — NOS2

Text-mined interactions from Literome

Nuedling et al., FEBS Lett 2001 : To define the role of ERbeta in the transcriptional activation of both endothelial ( eNOS ) and inducible nitric oxide synthase (iNOS) in cardiac myocytes, we used the complete ER-specific antagonist R, R-tetrahydrochrysene ( R, R-THC ) ... Taken together, these results show that ERbeta mediates transcriptional activation of eNOS and iNOS by E2
Zhu et al., Science 2002 (Hypertension) : In wild-type mouse blood vessels, estrogen attenuates vasoconstriction by an ERbeta mediated increase in inducible nitric oxide synthase expression
Simoncini et al., Arterioscler Thromb Vasc Biol 2003 : By interacting with phosphatidylinositol 3-kinase (PI3K), estrogen receptor (ER) alpha leads to activation of protein kinase Akt and to subsequent increase in endothelial nitric oxide synthase activity
Cignarella et al., J Pharmacol Exp Ther 2009 (Diabetes Mellitus, Experimental...) : Distinct roles of estrogen receptor-alpha and beta in the modulation of vascular inducible nitric-oxide synthase in diabetes
Fan et al., J Steroid Biochem Mol Biol 2009 : The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS