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KLF4 — NOS2

Text-mined interactions from Literome

Feinberg et al., J Biol Chem 2005 (Inflammation) : The KLF4 induction of the iNOS promoter is mediated by two KLF DNA binding sites at -95 and -212 bp, and mutation of these sites diminished induction by IFN-gamma and LPS
Kaushik et al., Journal of neuroinflammation 2012 (Disease Models, Animal...) : According to our earlier findings, Krüppel-like factor 4 (Klf4) , a zinc finger transcription factor, is involved in microglial activation and subsequent release of proinflammatory cytokines, tumor necrosis factor alpha, macrophage chemoattractant protein-1 and interleukin-6 as well as proinflammatory enzymes, inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide treated microglial cells