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BCL2 — IGF2
Text-mined interactions from Literome
Hung et al., Journal of neurosurgery. Spine 2007
(Disease Models, Animal...) :
Furthermore,
IGF-I attenuated caspase-9 cleavage,
increased Bcl2 , and thus inhibited apoptosis after SCI
Hilmi et al., J Invest Dermatol 2008
(Melanoma) :
Accordingly,
IGF1 increases the mRNA levels and protein expression of antiapoptotic members of the BCL2 family --
BCL2 and BCL-X ( L ) -- and that of the inhibitor of apoptosis protein, survivin
Singh et al., Growth Factors 2008
(Breast Neoplasms) :
Precursor
IGF-II ( proIGF-II ) and mature IGF-II ( mIGF-II )
induce Bcl-2 And Bcl-X L expression through different signaling pathways in breast cancer cells ... Furthermore,
IGF-II differentially
regulated the intracellular translocation of
Bcl-2 and Bcl-X ( L ), a critical process in breast cancer progression to hormone-independence
Singleton et al., J Biol Chem 1996
:
Finally, increased neuronal
IGF-IR expression
enhances the negative death regulator
Bcl-xL