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ICAM2 — NFKB1
Text-mined interactions from Literome
Brand et al., Gastroenterology 1999
:
Stimulation of
ICAM expression is
mediated by activation of the transcription factor
NF-kappaB
Li et al., J Immunol 2003
:
In surviving cells, TRAIL activates
NF-kappaB ,
induces expression of E-selectin,
ICAM-1 , and IL-8, and promotes adhesion of leukocytes
Mullan et al., Arthritis Rheum 2006
(Arthritis, Rheumatoid...) :
A-SAA induced expression of VCAM-1,
ICAM-1 , and MMP-1 was
down-regulated by
NF-kappaB inhibition
Reed et al., Dig Dis Sci 2005
(Colitis...) :
Colon tissue was collected for assessment of histological changes,
NF-kappa B activation , myeloperoxidase (MPO) activity, and expression of NK-1R, SP, TNFalpha, IL-1beta, VCAM-1,
ICAM-1 , E-selectin, CINC-1, MIP-1alpha, and iNOS
Bolick et al., Arterioscler Thromb Vasc Biol 2006
:
Inhibition of rhoA and PKCalpha significantly reduced
NF-kappaB activation,
ICAM-1 induction , and monocyte adhesion to aorta
Yi et al., Inflamm Res 2006
(Endotoxemia...) :
Lung injury score, lung wet-to-dry weight ( W/D ) ratio, percentage of neutrophils ( PMNs ) in BALF, lung permeability index (LPI),
intercellular adhesion molecule-1 ( ICAM-1 ) expression and
activation of
nuclear factor-kappa B (NF-kappaB) in the lungs were determined
Crispen et al., Prostate 2007
(Neoplasm Invasiveness...) :
Treatment with alpha-tocopherol succinate ( VES )
inhibits NF-kappaB but augments AP-1 activity, reduces expression of IL-6, IL-8, and VEGF, suppresses cell adhesion,
ICAM-1 and gp130 expression in androgen independent PC-3, DU-145, and CA-HPV-10 cells
Ishizuka et al., J Pharmacol Exp Ther 2008
:
Inhibition of
NF-kappaB activation and inhibition of ERK1/2 phosphorylation
inhibited 20-HETE induced
ICAM expression
Cepinskas et al., Am J Physiol Gastrointest Liver Physiol 2008
(Disease Models, Animal...) :
Induction of CLP resulted in increased PMN accumulation,
ICAM-1 expression, and
activation of
NF-kappaB in the liver of septic mice