Gene interactions and pathways from curated databases and text-mining

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CDK2 — NAB1

Text-mined interactions from Literome

Kobayashi et al., Nutr Cancer 2003 (Adenocarcinoma...) : A second objective was to determine whether NaB similarly affected the cyclin dependent kinase inhibitor, p21WAF1/CIP1
Li et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2004 (Myelodysplastic Syndromes) : The results showed that NaB and/or ATRA blocked cells mainly in the G0/G1 phase of the cell cycle ; ATRA inhibited the mRNA expression of CDK6, CDK4, cyclin D3 and cyclin D1 ; NaB inhibited the mRNA expression of CDK2, cyclin D2 and cyclin D1 ; ATRA and NaB inhibited the mRNA expression of CDK6, CDK4, CDK2 , cyclin D1, cyclin D2 and cyclin D3 ; ATRA and/or NaB both stimulated p21 expression at the mRNA levels