Fiordalisi et al., Cancer Res 2006
(Adenocarcinoma...) :
Catalytic PRL-3 mutants ( C104A or D72A ) were impaired in PRL-3 induced invasion and Rho activation, indicating that these properties require phosphatase activity
Fiordalisi et al., PloS one 2013
:
Src Mediated Phosphorylation of the Tyrosine Phosphatase PRL-3 Is Required for PRL-3 Promotion of Rho Activation, Motility and Invasion