Gene interactions and pathways from curated databases and text-mining

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BCL2 — SETBP1

Text-mined interactions from Literome

Hildeman et al., Immunity 2002 : We found that, in response to SEB , activated T cells died in vivo in the absence of Fas or TNF-R signaling but not when they overexpressed human Bcl-2
Lin et al., Allergy 2007 (Dermatitis, Atopic) : SEB-reactive ( TCRVbeta3+, Vbeta12+, and Vbeta17+ ) CD4+ T cells from AD patients were more resistant to SEB induced caspase-3 activation and SEB induced decrease of Bcl-2 and Bcl-2 mRNA than those from healthy subjects ... Exogenously added IL-4 inhibited SEB induced caspase-3 activation and SEB induced decrease of Bcl-2 and Bcl-2 mRNA in SEB-reactive CD4+ T cells from healthy subjects ... Inhibition of endogenous IL-4 by using anti-IL-4 neutralizing antibodies up-regulated SEB induced caspase-3 activation and SEB induced decrease of Bcl-2 and Bcl-2 mRNA in SEB-reactive CD4+ T cells from AD patients