Gene interactions and pathways from curated databases and text-mining

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F2RL1 — IRF6

Text-mined interactions from Literome

Jesmin et al., Thromb Haemost 2004 (Respiratory Distress Syndrome, Adult) : Expressions of PAR-2 , -3, and -4 were also increased by LPS with different time courses from PAR-1 expression
Ramachandran et al., Am J Physiol Lung Cell Mol Physiol 2007 : Flow cytometry for PAR1, PAR2, and PAR3 also demonstrated selective PAR2 upregulation in response to TNF-alpha and LPS
Ostrowska et al., Biochem Biophys Res Commun 2008 : Thrombin, PAR-2 activating peptide and LPS , were tested alone and in combination
Williams et al., Journal of signal transduction 2011 : Our results support the notion that PAR-2 plays a role in LPS activation of TLR4 signaling in macrophages