Gene interactions and pathways from curated databases and text-mining

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IRF6 — TPGS2

Text-mined interactions from Literome

Gilbert et al., J Cell Physiol 1993 : LPS is a potent inducer of mac-NOS in Swiss 3T3 cells but can not induce TIS10/PGS-2
Reddy et al., J Leukoc Biol 1994 : While TGF-beta alone has no effect on expression from the TIS10/PGS-2 gene, this cytokine inhibits LPS induced TIS10/PGS-2 protein accumulation and synthesis, as well as LPS induced TIS10/PGS-2 message accumulation in RAW 264.7 cells ... TGF-beta inhibits the LPS induced accumulation of TIS10/PGS-2 protein and message in cultured murine peritoneal macrophages, as well as in macrophage cell lines