Gene interactions and pathways from curated databases and text-mining

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CCDC88A — PARP1

Text-mined interactions from Literome

Peddi et al., Toxicology 2006 : PARP1 's binding to the cleaved DNA was inhibited, and PARP1 activation was suppressed by the wild-type APE1 , but not by the R177A mutant APE1 protein
Nho et al., J Ethnopharmacol 2011 : When we measured the affect of APE on intracellular signaling, APE stimulated the apoptotic factors bcl-2, bcl-xl, mcl-1, XIAP, BID, BIK, caspase-3, caspase-9 and PARP in HepG2 cells