Gene interactions and pathways from curated databases and text-mining

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IFI27 — PDGFB

Text-mined interactions from Literome

Zhan et al., Arterioscler Thromb Vasc Biol 2002 : Ad-DN-c-Jun attenuated PDGF-BB induced downregulation of p27 ( Kip1 ), as shown by Western blot analysis, and the prevented PDGF-BB induced decrease in cyclin E/cyclin dependent kinase 2 complex associated p27 ( Kip1 ), as shown by immunoprecipitation study
Sakakibara et al., J Biol Chem 2005 (MAP Kinase Signaling System) : PDGF-BB regulates p27 expression through ERK dependent RNA turn-over in vascular smooth muscle cells ... In summary, our data suggest that p27 is down-regulated by PDGF-BB in vascular smooth muscle cells through an ERK dependent posttranscriptional mechanism
Abid et al., J Biol Chem 2005 (Hyperplasia) : PDGF-BB, tumor necrosis factor-alpha, and insulin-like growth factor 1 treatment resulted in the nuclear exclusion of FoxO, whereas PDGF-BB alone down-regulated the FoxO target gene, p27 ( kip1 ), and enhanced cell survival and progression through the cell cycle
Xu et al., Clin Exp Pharmacol Physiol 2011 : In addition, TSG suppressed PDGF-BB induced downregulation of p27 and upregulation of p21, as well as PDGF-BB induced activation of ERK1/2