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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to FST

FST — GDF11

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: GDF11 → FST (decreases)
    Evidence: follistatin and deacetylase inhibitors follistatin is a secreted protein that interacts with and inhibits the activity of several TGFB family members including GDF11

Text-mined interactions from Literome

Gamer et al., Dev Biol 1999 : Interestingly, the activin antagonist, follistatin , but not noggin, an antagonist of BMPs 2 and 4, inhibited BMP-11 activity on animal caps
Gamer et al., Dev Biol 2001 : In addition, GDF11 induced the expression of its own antagonist follistatin , indicating that the activity of GFD11 may be limited by a negative feedback mechanism