Gene interactions and pathways from curated databases and text-mining

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CR1 — IL8

Text-mined interactions from Literome

Detmers et al., J Immunol 1991 : NAP-2, melanoma growth stimulatory activity, and two forms of NAP-1/IL-8 ( ser-NAP-1/IL-8 and ala-NAP-1/IL-8, consisting of 72 and 77 amino acids, respectively ), each caused an increase in the expression of CD11b/CD18 ( CR3 ) and CR1 , which was accompanied by a decrease in the expression of leukocyte adhesion molecule-1 ( LAM-1, LECAM-1 )
Knowles et al., Surgery 1995 (Anoxia) : Hypoxemia increased IL-8 stimulated PMN expression of CD32w and CD35 ( MCF CD32w, 791 +/- 105 versus 336 +/- 81 ; MCF CD35, 542 +/- 87 versus 254 +/- 41 ; p < 0.05 )
Knowles et al., Am J Physiol 1997 (Anoxia) : During reoxygenation, both whole blood PMN phagocytosis and bactericidal activity were reduced in the presence of IL-8 , TNF-alpha, or IL-1beta, and in subsets of PMN with reduced phagocytosis H/R reduced CD64, CD32w, CD16, CD35 , and CD11b/CD18 expression in the presence of each cytokine
Lothian et al., Biol Neonate 1997 : Both fMLP and IL-8 increased CD35 expression more markedly in adults