Gene interactions and pathways from curated databases and text-mining

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IRF6 — LOX

Text-mined interactions from Literome

Desender et al., Plant Biol (Stuttg) 2006 : In tobacco, LOX activity was not triggered by either LPS , but significantly increased following treatment with laminarin
Mao et al., Cancer prevention research (Philadelphia, Pa.) 2008 (Carcinoma...) : Exogenous LTB4 inhibited LPS induced 5-LOX activity and accentuated the down-regulation of 5-LOX mRNA, whereas suppression of 5-LOX abrogated the LPS induced changes, suggesting a negative feedback mechanism
Bonvissuto et al., Urology 2011 (Inflammation...) : LPS stimulation produced a proinflammatory phenotype in rat peritoneal MFs. LY, Se, and SeR inhibited the inflammatory cascade, but the Ly-Se-SeR association caused a greater inhibitory effect on the expression of COX-2, 5-LOX , and iNOS