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IFI27 — MYLIP
Text-mined interactions from Literome
le Sage et al., EMBO J 2007
(Neoplasms) :
Regulation of the
p27 ( Kip1 ) tumor suppressor by
miR-221 and miR-222 promotes cancer cell proliferation
Igoucheva et al., Biochem Biophys Res Commun 2009
(Melanoma...) :
Moreover, a series of functional assays demonstrated that
mir-221 could directly
inhibit cKit,
p27 ( Kip1 ) and, possibly, other pivotal proteins in melanoma
Corbetta et al., Endocr Relat Cancer 2010
(Adenoma...) :
Finally,
miR-296 and miR-222 levels negatively correlated with mRNA levels of the hepatocyte growth factor receptor
regulated tyrosine kinase substrate and
p27/kip1 levels respectively
Lu et al., Blood 2011
:
Silencing of
miR-221 or overexpressing of miR-155 in DCs
resulted in
p27 ( kip1 ) protein increase and DC apoptosis ... Furthermore, we provide evidence that
miR-155 indirectly
regulated p27 ( kip1 ) protein level by targeting Kip1 ubiquitination promoting complex 1
Sun et al., Mol Cancer Ther 2012
(Stomach Neoplasms) :
Luciferase assays revealed that
miR-196a inhibited
p27 ( kip1 ) expression by targeting one binding site in the 3'-untranslated region ( 3'-UTR ) of p27 ( kip1 ) mRNA
Wang et al., FEBS Lett 2013
(Retinoblastoma) :
Furthermore, overexpression of
miR-365b-3p upregulates p21 and
p27 but downregulates cdc2 and Cyclin D1 protein levels